From an EEG-based brain response to an objective brain-function measure.
An event-related potential (ERP) is a brain response time-locked to a specific event — an objective signal of a specific cognitive or affective process, extracted from the EEG.
From continuous EEG to an averaged response.
An event-related potential (ERP) is a brain response time-locked to an event — the onset of a stimulus. A single response is buried in ongoing EEG — but averaging many time-locked epochs cancels unrelated activity and the response emerges, evaluated by its polarity, latency and amplitude. In the oddball, a rare target elicits a large P300 ~300 ms after onset. Scroll to watch it build, step by step.
- 01 — AcquireContinuous EEGDry electrodes stream microvolt-scale activity from the scalp.
- 02 — Time-lockMark each onsetEvery stimulus onset defines an epoch — a short window around the event.
- 03 — Overlay & averageThe averaged ERP emergesMany target epochs are superimposed; averaging cancels the noise and the objective ERP remains.
Multiple ERPs to assess cognitive profiles.
The UB ERP System captures a battery of task-evoked ERPs and extracts their components across cognitive domains — reward, emotion, attention and cognitive control — benchmarking each person against a reference population.
RewP / FRN*
Frontocentral response to gains vs. losses; indexes reward sensitivity.
P300
Parietal positivity peaking ~300 ms; indexes attention & context updating.
LPP*
Sustained positivity to emotional stimuli; indexes affective attention.
N2 · ERN*
Frontocentral response to errors & conflict; indexes cognitive control.
* RewP / FRN, LPP and N2 · ERN are for investigational use only and have not been cleared by the US FDA; only P300 ERP measurement has been cleared.
Explore the peer-reviewed evidence on the Research page. →
Where objective ERP measurement is being studied.
Our research program applies task-evoked ERPs across psychiatric domains — validating biomarkers, subtypes and response prediction. These are investigational directions, distinct from the cleared indications.
Treatment-Resistant Biomarker Data Collection
Primary objective — A predictive treatment-resistant marker from baseline EEG/ERP to flag patients unlikely to respond to standard therapy.
Brain Function Measurement Based Care (RCT)
Primary objective — Show that brain-function feedback improves patient engagement, adherence, and clinical outcomes in depression care.
Objective endpoints for drug development
Primary objective — Task-evoked ERPs as objective, placebo-separating endpoints to de-risk CNS clinical trials.
Benchmarking each person against a reference population, subtype classification (neurotyping) and treatment-response prediction are areas of ongoing research. These features are for investigational use only and have not been cleared by the US FDA.
Bring objective brain measurement to your practice or pipeline.
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